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OCR: n levels of Hyperlipidaemia, defined as an increase oth, is one plasma cholesterol or triglyceride, or of that of the most common metabolic disorder s from occurs in industrialised societies. It resu e genetic and acquired derangements in th major metabolism of plasma lipoproteins. The rly significance of hyperlipidaemia, particul the main hypercholesterolaemia, is that it is one ature risk factors for the development of pren ith the atherosclerotic complications (Fig. 6.1), v lar risk principal lipoprotein-related cardiovasc ity factors being increased levels of low-den -density lipoproteins (LDL) and low levels of hig lipoproteins (HDL). The role of hore hypertriglyceridaemia as a risk factor is r cause, complex and may be related more to the rather than to the extent, of the conditio